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Updated: May 7, 2026

07:06
Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
11.2K
Design and additive manufacture for flow chemistry
Andrew J Capel1, Steve Edmondson, Steven D R Christie
1Department of Materials, Loughborough University, Loughborough, LE11 3TU, UK. S.Edmondson@lboro.ac.uk.
Lab on a Chip
|October 9, 2013
Summary
Additive manufacturing (AM) offers a novel approach for producing microreactors. This review covers five AM techniques used to create and test miniaturized reactors for various chemical reactions.
Area of Science:
- Chemical Engineering
- Materials Science
- Manufacturing Technology
Background:
- Miniaturized reactor systems offer advantages in reaction control and efficiency.
- Additive Manufacturing (AM) presents a novel approach for fabricating complex micro-scale devices.
Purpose of the Study:
- To review the application of AM techniques for producing milli-scale reactor systems.
- To evaluate the suitability of various AM methods for microreactor fabrication.
Main Methods:
- Review of five established AM techniques: stereolithography (SL), multi-jet modelling (MJM), selective laser melting (SLM), laser sintering (LS), and fused deposition modelling (FDM).
- Manufacturing of miniaturized reactors using the selected AM techniques.
- Testing of manufactured reactors with organic and inorganic reactions.
Main Results:
- Demonstration of AM's capability to produce functional milli-scale reactors.
- Successful application of SL, MJM, SLM, LS, and FDM in microreactor fabrication.
- Validation of reactor performance across diverse chemical reaction types.
Conclusions:
- Additive Manufacturing is a viable and versatile technology for the production of milli-scale reactor systems.
- The selection of AM technique depends on specific design requirements and material properties.
- Further research can optimize AM processes for enhanced microreactor performance.

