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Related Experiment Video

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Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

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Angiokeratomas - When is a few too many?

Colm O'Mahony¹, Andrea Franks, Rhiannon Llewellyn

¹Department of Sexual Health & HIV, Countess of Chester Hospital, Chester, UK.

International Journal of STD & AIDS

|October 10, 2013

Summary

A few angiokeratoma are normal, but numerous lesions may indicate Fabry disease. Genetic screening and family history are crucial for diagnosis when lesions are widespread.

Keywords:

Fabry disease Sexual health alpha galactosidase angiokeratoma genital

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Area of Science:

Dermatology
Genetics
Vascular Medicine

Background:

Angiokeratoma are benign vascular lesions that can appear on the skin.
Their presence can sometimes be associated with underlying systemic conditions.

Observation:

Many individuals present with a small number of scattered angiokeratoma.
A higher density or numerous angiokeratoma lesions warrant further medical investigation.

Findings:

The occurrence of numerous angiokeratoma should raise suspicion for Fabry disease, a rare genetic disorder.
Checking the family history is an essential step in evaluating potential cases.

Implications:

Early consideration of Fabry disease based on skin findings can lead to timely diagnosis and management.
This highlights the importance of dermatological examination in identifying potential genetic conditions.