Actin localization in rat ventral prostate glandular cells with an immunogold staining technique

Actin immunoreactive sites have been localized in rat ventral prostate secretory cells at electron microscope level by an immunogold staining technique. The labelling was found over the cell web, within the microvilli, in association with the apical plasma membrane and junctional complex. Immunogold staining was also found closely associated with the secretory granules limiting membrane. These results suggest that actin besides its role in the orientation and motility of microvilli may participate in the exocytosis process of the rat ventral prostate secretory granules.