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Autoimmune Disorders

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Related Experiment Video

Updated: May 7, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry

Published on: June 26, 2018

Autoimmune attack takes your breath away.

Tamsin M Lindstrom¹, William H Robinson

¹Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, CCSR, 269 Campus Drive, Stanford, CA 94305, USA.

Science Translational Medicine

|October 11, 2013

Summary

This summary is machine-generated.

Autoimmune reactions targeting lung proteins can lead to interstitial lung disease. This research explores the connection between lung-specific protein autoimmunity and this serious lung condition.

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Area of Science:

Immunology
Pulmonology
Pathology

Background:

Interstitial lung disease (ILD) encompasses a group of lung disorders.
Autoimmune conditions involve the immune system mistakenly attacking the body's own tissues.

Purpose of the Study:

To investigate the role of autoimmune responses against lung-specific proteins in the development of interstitial lung disease.

Main Methods:

Utilized data from Shum et al. (this issue).
Examined mechanisms of autoimmune targeting of lung-specific proteins.

Main Results:

Demonstrated that autoimmune targeting of a lung-specific protein is a cause of interstitial lung disease.

Conclusions:

Autoimmunity directed at lung-specific proteins is a significant factor in the pathogenesis of interstitial lung disease.