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Updated: May 7, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Xeroderma pigmentosum with melanoma of face and its prosthetic management
1Department of Prosthetics, de'Montmorency College of Dentistry / Punjab Dental Hospital, Lahore.
Abstract:
Xeroderma pigmentosum is a rare genetic disorder, characterized by cutaneous, ocular and neurological symptoms. Squamous cell carcinoma and melanoma are also its secondary characters. This case report is about maxillofacial prosthetic management of a 10 years old child presented with xeroderma pigmentosum. The nose of the patient was excised surgically due to melanoma. This case report elaborates the role of prosthodontist and the whole procedure of constructing the nasal prosthesis via conventional technique by using the patient's sibling nasal form as template. Regular follow up revealed marked improvement in esthetics, function and ultimately patient's quality of life.
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