Related Experiment Video
Updated: May 7, 2026
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Dietary patterns and suicide in Japanese adults: the Japan Public Health Center-based Prospective Study
Akiko Nanri1, Tetsuya Mizoue, Kalpana Poudel-Tandukar
1Akiko Nanri, PhD, Tetsuya Mizoue, MD, PhD, Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo; Kalpana Poudel-Tandukar, PhD, Waseda Institute for Advanced Study (WIAS), Waseda University, Tokyo; Mitsuhiko Noda, MD, PhD, Department of Diabetes and Metabolic Medicine, National Center for Global Health and Medicine, Tokyo; Masayuki Kato, MD, PhD, Japan Foundation for the Promotion of International Medical Research Cooperation, Tokyo; Kayo Kurotani, PhD, Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo; Atsushi Goto, MD, PhD, Department of Diabetes and Metabolic Medicine, National Center for Global Health and Medicine, Tokyo; Shino Oba, PhD, Department of Health Promotion, National Institute of Public Health, Saitama; Manami Inoue, MD, PhD, Shoichiro Tsugane, MD, PhD, Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.
Background:
Although dietary patterns have been linked to depression, a frequently observed precondition for suicide, no study has yet examined the association between dietary patterns and suicide risk.
Aims:
To prospectively investigate the association between dietary patterns and death from suicide.
Method:
Participants were 40 752 men and 48 285 women who took part in the second survey of the Japan Public Health Center-based Prospective Study (1995-1998). Dietary patterns were derived from principal component analysis of the consumption of 134 food and beverage items ascertained by a food frequency questionnaire. Hazard ratios of suicide from the fourth year of follow-up to December 2005 were calculated.
Results:
Among both men and women, a 'prudent' dietary pattern characterised by a high intake of vegetables, fruits, potatoes, soy products, mushrooms, seaweed and fish was associated with a decreased risk of suicide. The multivariable-adjusted hazard ratio of suicide for the highest v. lowest quartiles of the dietary pattern score was 0.46 (95% CI 0.28-0.75) (P for trend, 0.005). Other dietary patterns (Westernised and traditional Japanese) were not associated with suicide risk.
Conclusions:
Our findings suggest that a prudent dietary pattern may be associated with a decreased risk of death from suicide.
Related Concept Videos
01:27Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
01:29Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
01:29Bias in Epidemiological Studies
02:59Cancer Prevention
Some...
01:30Bulimia Nervosa
01:20Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...