A "dial-a-receptor" dynamic combinatorial library
Saleh Hamieh1, Vittorio Saggiomo, Piotr Nowak
1Centre for Systems Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen (The Netherlands) http://www.otto-lab.com.
Angewandte Chemie (International Ed. in English)
|October 12, 2013
Abstract:
Making receptors to order: A small dynamic combinatorial library (DCL), formed from two dithiols in water, provides a continuous range of six receptors of different sizes. The majority of the 30 tested amines and ammonium ions amplified receptors from this library, thus spanning the complete receptor-size range and showing that this DCL provides a generic platform for the development of receptors for this important class of compounds.
Keywords:
combinatorial chemistryhost-guest systemsmolecular recognitionnoncovalent interactionssupramolecular chemistryMore Related Videos
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