Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-term Depression01:05

Long-term Depression

27.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
27.3K
Long-term Depression01:03

Long-term Depression

2.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
2.6K
Depression: Overview01:18

Depression: Overview

1.2K
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
1.2K
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

2.2K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.2K
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

1.3K
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.3K
Repressed Memory01:16

Repressed Memory

672
Repressed memories are a psychological phenomenon where memories of traumatic events are unconsciously blocked from a person's awareness. This process occurs as a defense mechanism, protecting the mind from the emotional impact of distressing or painful experiences. For example, a person who has experienced childhood trauma may grow up with no conscious recollection of the event. In such cases, the memories are thought to be buried deep within the subconscious, inaccessible to the conscious...
672

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and target engagement of dopamine agonist pramipexole for anhedonic depression: a randomized placebo-controlled trial.

Nature medicine·2026
Same author

Author Correction: Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects.

Communications medicine·2026
Same author

A Secondary Analysis of Longitudinal Pilot-Study Data Investigating the Associations Between Health-Related Quality of Life and Executive Functions in Remitted Major Depressive Disorder and Developments Two-Years Following Cognitive Training.

Scandinavian journal of psychology·2025
Same author

Physical exercise augments cognitive behaviour therapy for older adults with generalized anxiety disorder: a randomized controlled trial.

Cognitive behaviour therapy·2025
Same author

Executive functioning in adolescents with internalizing disorders: a systematic review.

European child & adolescent psychiatry·2025
Same author

Effects of electroconvulsive therapy on hippocampal longitudinal axis and its association with cognitive side effects.

Communications medicine·2025

Related Experiment Video

Updated: May 7, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.4K

Verbal memory functioning in recurrent depression during partial remission and remission-Brief report.

Asa Hammar1, Guro Ardal

  • 1Department of Biological and Medical Psychology, University of Bergen Bergen, Norway ; Division of Psychiatry, Haukeland University Hospital, University of Bergen Bergen, Norway ; Moodnet Research Group, Haukeland University Hospital, University of Bergen Bergen, Norway.

Frontiers in Psychology
|October 12, 2013
PubMed
Summary

Patients with major depressive disorder (MDD) in remission show intact verbal memory, but struggle with immediate recall. Repetition of material improves memory performance in these individuals.

Keywords:
cognitive functiondepressionpartial remissionremissionverbal memory

More Related Videos

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
11:30

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

9.6K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.0K

Related Experiment Videos

Last Updated: May 7, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.4K
Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection
11:30

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Published on: August 26, 2011

9.6K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.0K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Major Depressive Disorder (MDD) is associated with cognitive deficits.
  • Verbal memory impairments are frequently reported in individuals with MDD.
  • The impact of remission status on verbal memory requires further investigation.

Purpose of the Study:

  • To examine verbal memory performance in patients with remitted and partially remitted MDD.
  • To compare the memory capabilities of MDD patients with healthy controls.

Main Methods:

  • Utilized the California Verbal Learning Test (CVLT) to assess verbal memory.
  • Included 31 patients diagnosed with MDD (remitted or partially remitted) and 31 matched healthy controls.

Main Results:

  • The MDD group demonstrated intact learning, recall, and recognition abilities.
  • A significant deficit was observed in immediate recall on the first trial compared to controls.
  • Memory performance improved when material was presented multiple times.

Conclusions:

  • Verbal memory in remitted and partially remitted MDD patients is generally preserved.
  • Immediate recall, particularly on initial exposure, may be a sensitive indicator of cognitive difficulties in MDD.
  • Repetition of information can enhance verbal memory recall in individuals with MDD, suggesting potential therapeutic strategies.