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Updated: May 7, 2026

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Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
Published on: December 15, 2023
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Synthetic cannabis and acute ischemic stroke
Miya E Bernson-Leung1, Lester Y Leung2, Sandeep Kumar2
1Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.
Summary
Synthetic cannabis use is linked to ischemic stroke in young adults. This study highlights a new association between synthetic cannabinoid use and stroke, even in healthy individuals.
Area of Science:
- Neurology
- Toxicology
Background:
- Previous research suggests a link between marijuana use and stroke.
- The health implications of synthetic cannabinoid compounds remain largely unknown.
Observation:
- Two young women experienced ischemic stroke within hours of using synthetic cannabis for the first time.
- Both patients presented with acute neurological deficits, including hemiplegia and aphasia.
Findings:
- Both cases involved large-territory infarctions of the right middle cerebral artery.
- Despite some individual risk factors, the patients were otherwise young and healthy.
Implications:
- Synthetic cannabis use should be considered in the evaluation of stroke in young adults.
- This association underscores the potential neurological risks associated with synthetic cannabinoid consumption.
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