[A clinical study on renal cell carcinoma].

Area of Science:

• Urology
• Oncology
• Nephrology

Context:

• Retrospective clinical review of 132 patients with renal cell carcinoma (RCC).
• Treatment period spanned from 1962 to 1983.
• Data collected on patient demographics, symptoms, metastasis, and survival outcomes.

Purpose:

• To analyze clinical characteristics and prognostic factors in a cohort of renal cell carcinoma patients.
• To evaluate survival rates and identify predictors of outcome in RCC.

Summary:

• The study included 132 patients (89 male, 44 female) aged 13-77 years (mean 57.3).
• Common symptoms were hematuria (55.4%), palpable mass (19.2%), and pain (13.8%).
• Distant metastasis occurred in 19.7% of patients, primarily to the lung (54%) and bone (19%).
• Overall 1, 3, and 5-year survival rates were 83.0%, 58.2%, and 56.9%, respectively.
• Prognosis was influenced by tumor site, patient age, ESR, CRP, alpha 2-globulin levels, and presence of distant metastasis.

Impact:

• Provides insights into the long-term clinical course and survival of renal cell carcinoma patients.
• Highlights key prognostic indicators for kidney cancer, aiding in risk stratification.
• Informs clinical management and research directions for renal cell carcinoma.