[Study on the screening program and risk factors of carotid artery stenosis with coronary artery disease]

The purpose of this research project was to evaluate the relationship and risk factors between coronary artery disease and carotid artery stenosis(CAS), screened by duplex ultra-sonography.

1339 patients with coronary artery disease were enrolled into this study. All patients performed carotid duplex ultra-sonography during hospitalization after coronary artery angiography.

The overall incidence of CAS was 11.8%(158/1339). Patients under older age and having history of stroke, the incidence rates were higher than other groups(P < 0.01, P = 0.02). The incidence of CAS in patients with multi-vessel lesions was higher than those of diseases involved in one vessel(χ(2) = 37.482, P < 0.01). CAS patients having left side major diseases, the incidence was higher than those of others(χ(2) = 38.93, P < 0.01). By multivariable logistic regression analysis, factors as:older age, having had history of stroke, with left side major disease and multivessel lesions etc. appeared to be independent predictors of CAS, respectively.

Patients with coronary artery diseases had higher prevalence rates for CAS when suffering from multi-vessel lesions or stenosis of left major stem. Factors as being elderly, having history of cerebro-vascular diseases were independent predictors of CAS in patients with coronary artery diseases.