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Updated: Aug 15, 2026

Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
Published on: July 6, 2019
Label-free quantitative imaging of cholesterol in intact tissues by hyperspectral stimulated Raman scattering
Ping Wang1, Junjie Li, Pu Wang
1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47906 (USA).
Abstract:
A finger on the pulse: Current molecular analysis of cells and tissues routinely relies on separation, enrichment, and subsequent measurements by various assays. Now, a platform of hyperspectral stimulated Raman scattering microscopy has been developed for the fast, quantitative, and label-free imaging of biomolecules in intact tissues using spectroscopic fingerprints as the contrast mechanism.
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