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Updated: May 6, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
Published on: May 9, 2025
[Etravirine in clinical practice: Experience in 151 non-naïve patients]
M Eulalia Valencia Ortega1, Victoria Moreno Celda, Germán Ramírez-Olivencia
1Servicio de Enfermedades Infecciosas, Hospital Carlos III, Madrid, España.
Background:
There are limited data on etravirine (ETV) use in routine clinical practice.
Methods:
The reasons, efficacy and tolerability of its use are retrospectively reviewed.
Results:
Overall, 151patients started a regimen containing ETV. The main reasons for prescription were toxicity and virological failure. After a median follow-up of 16months 76.2% of the patients had an undetectable viral load. Patients with detectable HIV-RNA at baseline had a greater risk of failure (31.7% vs 18%; P=.05).
Conclusion:
ETV is safe, effective and durable.
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