Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

48
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
48
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

1.1K
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
1.1K
Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

2.0K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
2.0K
Viral Meningitis01:18

Viral Meningitis

219
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
219
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

45
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
45
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

32
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
32

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative alignment and risk of proximal junctional failure : a framework for upper instrumented vertebra selection in adult spinal deformity.

The bone & joint journal·2026
Same author

Machine Learning-Based Prediction of Independent Ambulation Following Intramedullary Spinal Cord Tumor Resection.

Neurosurgery·2026
Same author

CNS-Obsidian: A Neurosurgical Vision-Language Model Built From Scientific Publications.

Neurosurgery·2026
Same author

Management of glioblastoma intramedullary spinal cord metastasis with advanced intraoperative techniques: a case series and systematic review.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

Late to Extubate? Risk Factors and Associations for Delayed Extubation After Adult Cervical Deformity Corrective Surgery.

Spine·2025
Same author

What's the harm? Evaluating complications associated with salvaged red blood cell transfusion in spinal deformity surgery: a nonrandomized controlled trial.

Journal of neurosurgery. Spine·2025
Same journal

Tumor control and cranial nerve outcomes after Gamma Knife radiosurgery for Glomus jugulare tumors: a systematic review, meta-analysis, and institutional failure pattern analysis.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Clinical utility of maximal and minimal intensity projections in T2-weighted MRI for neurosurgical planning.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Clinical and CT perfusion outcomes after direct STA-MCA bypass in moyamoya and non-moyamoya steno-occlusive disease: an Indonesian single-center cohort.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Effect of non-consecutive treatment during hypofractionated stereotactic radiosurgery (HF-SRS) for brain metastases.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Pre- and postoperative cranial shape analysis in Craniosynostosis: The role of mechanical loading during CT imaging.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same journal

Spontaneous Recanalization of Thrombus on Ultra-High field Strength MRI.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
See all related articles

Related Experiment Video

Updated: May 6, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

1.1K

Holospinal epidural abscess.

Darryl Lau1, John Maa2, Praveen V Mummaneni1

  • 1Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143-0112, USA.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 17, 2013
PubMed
Summary
This summary is machine-generated.

Holospinal epidural abscess (HEA), a rare spinal condition, can cause severe myelopathy. Prompt surgical decompression and drainage led to significant neurological recovery in two patients.

Keywords:
DecompressionEpidural abscessHolospinalLaminectomySpine

More Related Videos

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

828
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

4.9K

Related Experiment Videos

Last Updated: May 6, 2026

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

1.1K
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

828
Intraoperative Ultrasound in Spinal Surgery
05:53

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

4.9K

Area of Science:

  • Neurosurgery
  • Spinal Surgery
  • Infectious Disease

Background:

  • Holospinal epidural abscess (HEA) is an exceptionally rare condition characterized by spinal epidural abscesses spanning the entire spine.
  • Spinal epidural abscesses can lead to severe neurological deficits, including myelopathy, if not treated promptly.

Observation:

  • Two patients presented with myelopathy attributed to holospinal epidural abscess.
  • Clinical presentation included symptoms indicative of spinal cord compression.

Findings:

  • Both patients underwent urgent surgical decompression and abscess drainage.
  • Neurological function significantly improved following surgical intervention.

Implications:

  • Early surgical management is crucial for favorable outcomes in HEA cases.
  • This case series contributes to understanding the surgical strategies for managing this rare condition.