Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

1.5K
The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
1.5K
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance01:23

Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance

936
The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
A study on guinea pigs examined the...
936
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

440
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
440
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

869
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
869
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

2.4K
Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
2.4K
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

404
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
404

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Academic Detailing Interventions and Evidence-Based Prescribing: A Systematic Review.

JAMA network open·2025
Same author

Development of PIVOT with MI: A motivational Interviewing-Based vaccine communication training for pediatric clinicians.

Vaccine·2023
Same author

"It's Like 1998 Again": Why Parents Still Refuse and Delay Vaccines.

Global pediatric health·2021
Same author

Long-acting Methylphenidate Induced Transient Orofacial Dyskinesia and Upper Extremity Choreoathetosis: A Case Report.

South Dakota medicine : the journal of the South Dakota State Medical Association·2021
Same author

A heuristic study of the similarities and differences in offender characteristics across potential and successful serial sexual homicide offenders.

Behavioral sciences & the law·2021
Same author

Motivational Interviewing for Maternal Immunisation (MI4MI) study: a protocol for an implementation study of a clinician vaccine communication intervention for prenatal care settings.

BMJ open·2020

Related Experiment Video

Updated: May 6, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
05:42

The Forced Swim Test as a Model of Depressive-like Behavior

Published on: March 2, 2015

39.0K

Escitalopram-associated acute urinary retention.

Dominick Trombetta1, Kathleen Garrett, Marissa Harrison

  • 1Department of Pharmacy Practice, Wilkes University Nesbitt School of Pharmacy College of Pharmacy and Nursing, Wilkes-Barre, Pennsylvania.

The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists
|October 17, 2013
PubMed
Summary

Selective serotonin-reuptake inhibitors like escitalopram can rarely cause acute urinary retention (AUR). This case highlights the need to consider SSRIs when AUR occurs, even if other medications are suspected.

Keywords:
5-HT = 5-hydroxytryptophanAUR = Acute urinary retentionAcute urinary retentionAnticholinergicsAntihistaminesCYP = CytochromeEscitalopramINR = International normalized ratioM1 = Muscarinic-1 receptorMDI = Metered-dose inhalerPVR = Postvoid residualsSSRI = Selective serotonin-reuptake inhibitorSelective serotonin reuptake inhibitorsUTI = Urinary tract infectionUrinary retention

More Related Videos

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
12:21

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

15.5K
Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
14:55

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

Published on: April 18, 2011

16.5K

Related Experiment Videos

Last Updated: May 6, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
05:42

The Forced Swim Test as a Model of Depressive-like Behavior

Published on: March 2, 2015

39.0K
Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
12:21

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

15.5K
Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
14:55

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI

Published on: April 18, 2011

16.5K

Area of Science:

  • Pharmacology
  • Urology

Background:

  • Acute urinary retention (AUR) is commonly linked to anticholinergic and antihistamine medications.
  • Selective serotonin-reuptake inhibitors (SSRIs) are not typically considered a cause of AUR.

Observation:

  • A patient developed AUR after the introduction of escitalopram.
  • Initial suspicion fell on ipratropium, which was discontinued without resolution of symptoms.
  • Urinary retention resolved only after discontinuing escitalopram.

Findings:

  • Escitalopram was identified as the likely cause of AUR in this patient.
  • Medical causes of urinary retention were ruled out.
  • The SSRI's role in AUR was initially overlooked.

Implications:

  • Clinicians should consider SSRIs, such as escitalopram, as a potential cause of AUR.
  • Rare adverse drug reactions, like SSRI-induced AUR, may be underreported.
  • Awareness of this potential side effect can improve diagnosis and patient management.