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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: May 6, 2026

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Published on: May 30, 2011

Arterial spin labeling with simultaneous multi-slice echo planar imaging.

David A Feinberg¹, Alexander Beckett, Liyong Chen

¹Helen Wills Institute of Neuroscience, University of California, Berkeley, Advanced MRI Technologies, Sebastopol, California, USA.

Magnetic Resonance in Medicine

|October 17, 2013

Summary

This summary is machine-generated.

Simultaneous multi-slice echo planar imaging (SMS-EPI) enhances 2D arterial spin labeling (ASL) by increasing brain coverage without longer scan times. This advancement allows for more comprehensive brain perfusion measurements.

Keywords:

ASL EPI GRASE PASL multiband simultaneous

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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Area of Science:

Magnetic Resonance Imaging
Neuroimaging
Biomedical Engineering

Background:

Arterial Spin Labeling (ASL) is a non-invasive MRI technique for measuring cerebral blood flow.
Traditional 2D ASL techniques are limited in slice coverage and acquisition speed.
Simultaneous Multi-Slice (SMS) imaging offers potential to accelerate MRI acquisition.

Purpose of the Study:

To integrate Simultaneous Multi-Slice (SMS) echo planar imaging (EPI) with 2D arterial spin labeling (ASL).
To assess the feasibility of SMS-EPI for increasing brain coverage in ASL imaging.
To evaluate the impact of SMS acceleration on image quality and acquisition time.

Main Methods:

Pulsed ASL (PASL) preparations (FAIR, QUIPSS II) were combined with SMS-EPI.
Testing was conducted in four subjects at 3 Tesla using multiband (MB) acceleration factors from MB-2 to MB-5.
Quantitative comparisons were made to conventional 2D PASL EPI and qualitative comparisons to 3D GRASE ASL.

Main Results:

SMS-EPI enabled acquisition of 20 slices in as little as 196 ms (MB-5), significantly reducing scan time compared to conventional EPI (874 ms).
Spatial Signal-to-Noise Ratio (SNR) remained comparable for lower acceleration factors (MB-2), while temporal SNR decreased with higher acceleration.
SMS-EPI ASL demonstrated differences compared to 3D GRASE ASL, particularly regarding susceptibility artifacts.

Conclusions:

SMS-EPI significantly increases slice coverage for 2D ASL imaging without extending acquisition time.
This technique offers a major advantage for comprehensive brain perfusion assessment.
SMS-EPI represents a valuable advancement for ASL neuroimaging.