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Ceftriaxone-induced hemolysis
Vivek S Guleria1, Nitin Sharma, Sagar Amitabh
1Department of Internal Medicine, Armed Forces Medical College, Pune - 411 040, India.
Abstract:
Immune hemolytic anemia is a rare adverse effect of ceftriaxone, a third-generation cephalosporin, which is a commonly used antibiotic. We describe a 60-years-old lady, a case of community-acquired pneumonia, who developed severe hemolysis after the first dose of ceftriaxone. Her hemoglobin dropped from 9.6 g /dl to 5.5 g /dl. However, she improved after discontinuation of the drug and blood transfusion. This report serves as a reminder to medical fraternity that life-threatening hemolysis can rarely follow administration of ceftriaxone.
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