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A novel and photostable pH probe for selectively staining nuclei in living cells
Lintao Zeng1, Ne Fan, Jiayu Zha
1Department of Chemistry and Material Sciences, Hubei Engineering University, Xiaogan 432000, P. R. China. zlt1981@126.com.
The Analyst
|October 17, 2013
Abstract:
A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift (122 nm) and good photostability. The probe responds to basic pH (pKa 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.

