Related Experiment Video
Updated: May 6, 2026

06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.7K
Squamous cell carcinoma in lichen planopilaris
Cristina Garrido Colmenero1, Aurelio Martín Castro, Ignacio Valenzuela Salas
1Dermatology Service, Hospital Virgen de Las Nieves, Granada, Spain;
Journal of Dermatological Case Reports
|October 18, 2013
Summary
Lichen planopilaris (LPP) is a rare hair follicle condition. Long-term LPP patients require monitoring for potential squamous cell carcinoma development.
Area of Science:
- Dermatology
- Oncology
Background:
- Lichen planopilaris (LPP) is a rare variant of cutaneous lichen planus.
- LPP primarily affects hair follicles, leading to potential scarring and alopecia.
Observation:
- A case study of an 87-year-old woman with cicatricial alopecia due to LPP is presented.
- Diagnosis was confirmed via clinical evaluation, histopathology, and trichoscopy.
- Squamous cell carcinoma developed in the alopecic area after 18 years of LPP progression.
Findings:
- The study highlights a potential association between lichen planopilaris and squamous cell carcinoma.
- Close monitoring of LPP patients is crucial, particularly those with long-standing disease.
Implications:
- Clinicians should consider the co-occurrence of LPP and squamous cell carcinoma.
- Vigilance for new lesions not typical for LPP is essential for early cancer detection in affected individuals.
Related Concept Videos
Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Papillary Dermis
5.9K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.9K
Cells of the Epidermis
7.3K
The epidermis is made of four or five layers of epithelial cells, depending on its location in the body. From deep to superficial, these layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum.
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
The cells in all these layers except the stratum basale are called keratinocytes, a type of cell that manufactures and stores the protein keratin. The keratinocytes in the stratum corneum are dead and regularly slough away, being replaced by cells from...
7.3K
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K

