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Updated: May 6, 2026

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Visible-light-promoted selenofunctionalization of alkenes
Elizabeth S Conner1, Katherine E Crocker, Ranelka G Fernando
1Department of Chemistry, Louisiana State University , Baton Rouge, Louisiana 70803, United States.
Abstract:
A visible-light-promoted method for the selenofunctionalization (and tellurofunctionalization) of alkenes has been developed. This method obviates the prepreparation of moisture-sensitive chalcogen electrophiles. The experimental setup is simple, and superior yields are obtained in the case of selenofunctionalization (up to 99%) while moderate to good yields are obtained in the case of tellurofunctionalization (53-75%). A variety of intra- and intermolecular processes and a short synthesis of the Amaryllidaceae alkaloid (±)-γ-lycorane are demonstrated with this method.
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