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Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

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Published on: June 14, 2021

Giant retinal tears.

Manoharan Shunmugam¹, Ghee Soon Ang², Noemi Lois³

¹The Tun Hussein Onn National Eye Hospital, Selangor, Malaysia.

Survey of Ophthalmology

|October 22, 2013

Summary

This summary is machine-generated.

Giant retinal tears (GRT) are significant retinal breaks affecting 1.5% of detachments, often managed with vitrectomy. Fellow eyes require monitoring due to higher risks of retinal tears and detachment.

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Area of Science:

Ophthalmology
Retinal Surgery

Background:

A giant retinal tear (GRT) is a severe retinal break involving at least three clock hours.
GRTs constitute 1.5% of rhegmatogenous retinal detachments, with higher incidence in males and 12.8% bilaterality.
Common causes include idiopathic factors, trauma, hereditary conditions, and high myopia.

Purpose of the Study:

To review the current understanding and management of giant retinal tears.
To discuss surgical outcomes and risks associated with GRTs.

Main Methods:

Review of existing literature on giant retinal tears.
Analysis of incidence, causes, and management strategies.
Evaluation of surgical outcomes and long-term prognosis.

Main Results:

Pars plana vitrectomy is the primary treatment for most GRTs.
Adjunctive scleral buckling and silicone oil tamponade show no clear long-term advantage over gas.
Primary and final retinal reattachment rates are high (88% and 95%), but visual recovery can be limited.
Fellow eyes have an increased risk of retinal tears and detachment.

Conclusions:

Vitrectomy is effective for GRT repair, with high reattachment rates.
Long-term visual outcomes and fellow eye risks necessitate careful monitoring and consideration of prophylactic treatments, though efficacy is unproven.