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Related Experiment Video

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Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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Phacovitrectomy versus Vitrectomy for Primary Rhegmatogenous Retinal Detachment in Phakic Eyes: A Multicenter

Melissa Gough1, Minahil Mujahid2, David Yorston3

  • 1Bioscience Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.

Ophthalmology. Retina
|March 22, 2026
PubMed
Summary

Phacovitrectomy and pars plana vitrectomy (PPV) offer comparable anatomical success for primary rhegmatogenous retinal detachment (RRD) repair in phakic eyes. Phacovitrectomy showed a slight visual acuity benefit, largely attributed to lens changes rather than retinal treatment effects.

Keywords:
CataractPars plana vitrectomyPhacovitrectomyRhegmatogenous retinal detachment.

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Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Vitreoretinal Interface

Background:

  • Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition requiring prompt surgical intervention.
  • Pars plana vitrectomy (PPV) and phacovitrectomy are surgical options for RRD repair in phakic eyes.
  • Comparing outcomes between PPV and phacovitrectomy is crucial for optimizing surgical strategies.

Purpose of the Study:

  • To compare the anatomical and visual outcomes of pars plana vitrectomy (PPV) versus phacovitrectomy for primary rhegmatogenous retinal detachment (RRD) repair in phakic eyes.
  • To evaluate postoperative complications associated with each surgical approach.

Main Methods:

  • A multicentre propensity score-matched cohort study utilizing the BEAVRS-EURETINA vitreoretinal database (2008-2024).
  • Included phakic eyes of patients aged >45 years undergoing primary RRD repair.
  • Primary anatomical success, visual acuity, and postoperative complications were assessed at ≥8 weeks follow-up.

Main Results:

  • Anatomical success exceeded 90% in both PPV and phacovitrectomy groups, with no significant difference between them in matched analyses.
  • Phacovitrectomy was associated with a small, statistically significant improvement in visual acuity, which attenuated after adjusting for baseline cataract.
  • Cystoid macular edema was more frequent after phacovitrectomy (1.94% vs. 0.35%), while epiretinal membrane rates were slightly higher after PPV.

Conclusions:

  • Phacovitrectomy provides anatomical outcomes comparable to PPV for primary RRD repair in phakic eyes.
  • The observed visual advantage with phacovitrectomy is likely related to cataract extraction rather than a direct retinal treatment effect.
  • Both procedures demonstrate high success rates, with specific complication profiles to consider.