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Published on: January 21, 2021
Neurological Complications in Controlled HIV Infection
Kate M Crossley1, Bruce J Brew
1Department of Neurology, St. Vincent's Hospital, Level 4 Xavier Building, 390 Victoria St Darlinghurst, Sydney, Australia.
Abstract:
In recent years, there have been great advances in therapies for human immunodeficiency virus (HIV) that have allowed suppression of the virus and its effects on the body. Despite this progress, neurological complications persist in HIV-infected individuals. In this review we consider the possible ways that HIV might cause neurotoxicity and neuroinflammation. We discuss the spectrum of neurological disorders caused by HIV and its treatment, with a particular focus on both HIV-associated neurocognitive disorders and peripheral neuropathies. Since there has been a shift to HIV being a chronic illness, we also review the increasing prevalence of cerebrovascular disease and neurodegenerative disorders.
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