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Bone marrow-derived myofibroblasts promote colon tumorigenesis through the IL-6/JAK2/STAT3 pathway

Liming Zhu1, Xiaojiao Cheng2, Yanfei Ding2

  • 1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

Cancer Letters
|October 23, 2013
PubMed

Keywords:
BMF conditioned mediumBMF-CMBMFsBone marrow-derived myofibroblastsCAFsCancer stem cellCo-culture-CMColon cancerEGFFLIL-6JAK2MSCsSTAT3TGF-βbFGFbasic fibroblast growth factorbone marrow-derived myofibroblastscancer-associated fibroblastsco-culture medium of BMFs and cancer cellsepithelial growth factorfirefly luciferaseinterleukin-6janus kinase 2mesenchymal stem cellssignal transducer and activator of transcription 3transformation growth factor-β

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