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Updated: May 6, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Metabolomics: integration of a new "omics" with clinical pharmacology
11] Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA [2] Clinical Pharmacology and Toxicology Section, Arkansas Children"s Hospital, Little Rock, Arkansas, USA.
Abstract:
The term "pharmacometabolomics" was coined in 2006 to reflect the potential of the predrug metabolomic signature to predict the postdrug response. Metabolomics can be used to examine the contribution of nongenomic factors, such as the environment, diet, or the gut microbiome, to the overall drug response. As such, the complexity of human biology afforded by metabolomics can complement genomic approaches, ultimately moving the discipline of clinical pharmacology closer to full implementation of personalized medicine.
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