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Involvement of the Choroid Plexus in Neurotuberculosis: MR Findings in Six Cases

A Bhattacharyya1, D K Boruah, A Handique

  • 1Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences; Lucknow, India - rphadke@sgpgi.ac.in.

The Neuroradiology Journal
|October 24, 2013
PubMed

Insights

Tuberculous meningitis rarely affects the choroid plexus, but this study highlights its key imaging features. This research presents the largest series of choroid plexus involvement in central nervous system tuberculosis.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Intracranial infections causing meningitis often originate in the choroid plexus, yet choroid plexus lesions are uncommon.
  • Tuberculous meningitis is a rare cause of choroid plexus involvement, with limited case reports available.

Purpose of the Study:

  • To describe the imaging characteristics of choroid plexus involvement in tuberculous meningitis.
  • To present the largest case series to date of this rare manifestation of central nervous system tuberculosis.

Main Methods:

  • Retrospective review of six patients with confirmed tuberculous involvement of the choroid plexus.
  • Analysis of imaging findings, including MRI and CT scans.

Main Results:

  • Common imaging findings included abnormal enhancement of a thickened choroid plexus.
  • Asymmetric hydrocephalus, sequestrated temporal horn, periventricular edema, and intraventricular septa formation were observed.
  • The study highlights the distinct radiological signs associated with this rare condition.

Conclusions:

  • Choroid plexus involvement in tuberculous meningitis, though rare, presents with characteristic imaging features.
  • Recognizing these imaging findings is crucial for the diagnosis of central nervous system tuberculosis.
  • This series contributes significantly to understanding the radiological spectrum of this uncommon presentation.

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