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Interfacial properties of three different bioactive dentine substitutes
Elizabeta S Gjorgievska1, John W Nicholson, Sonja M Apostolska
1Faculty of Dental Medicine, University "Sts Cyril and Methodius" Skopje 1000, Republic of Macedonia.
Summary
Glass-ionomer and calcium-silicate cements show promise as bioactive dentine substitutes for tooth repair. Bioglass exhibited poor adaptation due to particle size, suggesting smaller particles may improve results.
Area of Science:
- Dental Materials Science
- Biomaterials Engineering
- Regenerative Dentistry
Background:
- Dentine substitutes are crucial for effective tooth repair.
- Bioactive materials offer potential for enhanced dentine regeneration and sealing.
- Evaluating novel biomaterials is essential for advancing restorative dental procedures.
Purpose of the Study:
- To compare the efficacy of glass-ionomer cement, particulate bioglass, and calcium-silicate cement as dentine substitutes.
- To assess the bioactivity and cavity adaptation of these materials in artificial caries models.
- To determine the suitability of these materials for complete tooth repair.
Main Methods:
- Class V cavities were prepared in 15 human molars and de-mineralized.
- Cavities were restored with Bioglass®45S5, Biodentine™, or ChemFil® Superior.
- Restored teeth were analyzed using scanning electron microscopy (SEM) and energy-dispersive X-ray analysis after 6 weeks in artificial saliva.
Main Results:
- Both glass-ionomer and calcium-silicate cements demonstrated ion exchange with tooth tissue, confirming bioactivity.
- Bioglass®45S5 showed poor cavity adaptation due to its particle size.
- Biodentine™ (calcium-silicate cement) provided an excellent seal via micromechanical attachment.
Conclusions:
- Glass-ionomer cement and calcium-silicate cement are effective dentine substitutes.
- Optimizing bioglass particle size may enhance its performance as a dentine substitute.
- Calcium-silicate cements offer superior sealing properties for tooth repair.

