Related Experiment Video
Updated: May 6, 2026

Flow Cytometric Analysis of Biomarkers for Detecting Human Sperm Functional Defects
Published on: April 21, 2022
Mammalian sperm fertility related proteins
Ali Ashrafzadeh1, Saiful Anuar Karsani, Sheila Nathan
11. School of Biosciences and Biotechnology, Faculty of Science and Technology, University Kebangsaan Malaysia, Selangor, Malaysia;
Abstract:
Infertility is an important aspect of human and animal reproduction and still presents with much etiological ambiguity. As fifty percent of infertility is related to the male partner, molecular investigations on sperm and seminal plasma can lead to new knowledge on male infertility. Several comparisons between fertile and infertile human and other species sperm proteome have shown the existence of potential fertility markers. These proteins have been categorized into energy related, structural and other functional proteins which play a major role in sperm motility, capacitation and sperm-oocyte binding. The data from these studies show the impact of sperm proteome studies on identifying different valuable markers for fertility screening. In this article, we review recent development in unraveling sperm fertility related proteins.
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