Pulmonary embolism as the first manifestation of multiple myeloma
N Vallianou1, V Lazarou, J Tzangarakis
1Internal Medicine Department, Evangelismos General Hospital, 45-47 Ipsilantou Street, 10676 Athens, Greece.
Abstract:
Multiple myeloma is considered a hypercoagulable state due to several mechanisms such as the increased IL-6 and immunoglobulins production, the defective fibrinolytic mechanism, and the acquired resistance to activated protein C that are involved in the pathogenesis and clinical futures of the disease. We describe a case of a female patient who presented to the hospital with pulmonary embolism as the first manifestation of the hypercoagulability of multiple myeloma.
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