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Related Experiment Videos

Fever in various rheumatic diseases.

A Weinberger, A Kesler, J Pinkhas

    Clinical Rheumatology
    |September 1, 1985
    PubMed
    Summary

    Fever is a common symptom in rheumatic diseases like rheumatoid arthritis and lupus. This review examines fever frequency and discusses the underlying mechanisms in various inflammatory conditions.

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    Area of Science:

    • Rheumatology
    • Immunology
    • Internal Medicine

    Background:

    • Fever is a frequent manifestation in numerous rheumatic diseases.
    • Understanding the prevalence and mechanisms of fever is crucial for diagnosis and management.
    • Rheumatic conditions encompass a wide spectrum of inflammatory and autoimmune disorders.

    Purpose of the Study:

    • To review the frequency of fever in specific rheumatic diseases.
    • To discuss the pathophysiological mechanisms contributing to fever in these conditions.
    • To provide a comprehensive overview of fever as a symptom in rheumatology.

    Main Methods:

    • Literature review of studies reporting fever incidence in rheumatic diseases.
    • Analysis of data on rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, crystal-induced arthritis, vasculitides, and sarcoidosis.
    • Discussion of proposed mechanisms for fever generation in inflammatory states.

    Main Results:

    • Fever occurs with varying frequency across different rheumatic diseases.
    • Specific conditions like vasculitides and systemic lupus erythematosus are frequently associated with fever.
    • Mechanisms involve inflammatory mediators and immune system activation.

    Conclusions:

    • Fever is a significant clinical feature in many rheumatic diseases.
    • Recognizing fever patterns aids in the diagnosis and understanding of disease activity.
    • Further research into fever mechanisms can inform therapeutic strategies.

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