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iChip

iChip

The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...

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Updated: May 6, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

Published on: April 12, 2018

A programmable and reconfigurable microfluidic chip.

Raphael Renaudot¹, Vincent Agache, Yves Fouillet

¹CEA-Leti, Minatec Campus, Grenoble, 38054, France. raphael.renaudot@cea.fr vincent.agache@cea.fr yves.fouillet@cea.fr guillaume.laffite@cea.fr.

|October 25, 2013

Summary

This summary is machine-generated.

This study introduces a novel method for rapidly fabricating reconfigurable microfluidic chips using digital microfluidics and paraffin. The system allows on-demand customization of microchannels for continuous-flow experiments.

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Last Updated: May 6, 2026

Reconfigurable Microfluidic Channel with Pin-discretized Sidewalls

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Published on: April 12, 2018

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Published on: April 17, 2021

Area of Science:

Microfluidics
Materials Science
Digital Microfluidics

Background:

Continuous-flow microfluidic chips are essential for various lab-on-a-chip applications.
Fabricating and reconfiguring microfluidic devices can be complex and time-consuming.
Existing methods often lack flexibility and cost-effectiveness.

Purpose of the Study:

To present a novel, rapid fabrication method for programmable and reconfigurable continuous-flow microfluidic chips.
To demonstrate a cost-effective and adaptable approach to microfluidic device design.
To enable on-demand customization of microchannel geometries.

Main Methods:

Utilizes a digital microfluidic platform with addressable electrodes.
Employs electrowetting on dielectric and liquid dielectrophoresis to pattern de-ionized water in liquid paraffin.
Integrates a thermoelectric cooler to solidify paraffin, forming microchannels defined by the water pattern.

Main Results:

Successfully fabricated continuous-flow microfluidic chips with programmable geometries.
Demonstrated the resettable and reversible nature of the paraffin microchannel formation.
Illustrated the concept with various basic and typical fluidic geometries.

Conclusions:

The developed method offers a rapid, cost-effective, and adaptable solution for microfluidic chip fabrication.
The programmable and reconfigurable nature of the microchannels enhances experimental flexibility.
This approach holds significant potential for advancing microfluidic applications and research.