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Updated: Apr 1, 2026
Author Spotlight: Improving Reproducibility in Vascular Organoids Using ROCK Inhibitors and Microwell Confinement
Published on: December 13, 2024
Using vascularized organoids-on-chip for assessing systemic drug delivery
Emily Tubbs1, Fabrice P Navarro2, Yves Fouillet2
1University Grenoble Alpes, CEA, Inserm, IRIG, UA13 BGE, Biomics, Grenoble, France.
None:
Vascularized organoids-on-chip aim at assessing systemic drug delivery, but also drug screening, toxicity testing, pharmacokinetics and dynamics, and disease modeling. Here, we provide a detailed experiment protocol to vascularize organoids-on-chip, in regards to pancreatic islet spheroids and hydrogel preparation towards the modelisation of autoimmune diseases, inflammation, immunotherapies.
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