Related Experiment Video
Updated: May 6, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
The implications and consequences of maternal obesity on fetal intrauterine growth restriction
L Radulescu1, O Munteanu, F Popa
1Biochemistry Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest.
Insights
Maternal obesity significantly increases risks for both mothers and newborns, leading to more intensive care needs and cesarean births. Early diagnosis of fetal growth restriction is crucial for managing these high-risk pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Health
- Public Health
Background:
- Rising rates of maternal obesity (BMI ≥ 30 kg/m2) present significant health challenges.
- Maternal obesity is linked to increased maternal and fetal complications, extending into childhood and adulthood.
- Understanding these risks is critical for improving pregnancy outcomes.
Purpose of the Study:
- To evaluate maternal and neonatal complications at birth in relation to maternal obesity.
- To identify specific risks associated with obesity during pregnancy.
Main Methods:
- Retrospective analysis of births at Bucharest University Emergency Hospital (2012).
- Data collected on maternal obesity, complications, and neonatal status (birth weight, Apgar score, etc.).
Main Results:
- Obese mothers had higher rates of intrauterine growth restriction (IUGR).
- Increased need for neonatal intensive care, higher cesarean surgery rates, and thromboembolic complications were observed.
- Complication severity correlated with the degree of maternal obesity.
Conclusions:
- Pregnancy complications increase in number and severity with rising maternal obesity.
- Early diagnosis and management of IUGR are vital for pregnancies affected by maternal obesity.
- Close collaboration among obstetricians, family physicians, and neonatologists is essential.
Context:
The prevalence of maternal obesity has been increasing dramatically in the recent years (body mass index ≥ 30 kg/m2). Maternal obesity is associated with an unequivocal increase in maternal and fetal complications of pregnancy and more than that, these complications also extend beyond fetal life in childhood and adulthood. Objective. The aim of this study was to evaluate maternal and neonatal complications at birth associated with maternal obesity.
Materials And Methods:
The study included all women who gave birth between January 1, 2012 and December 31, 2012 at Bucharest University Emergency Hospital. Collected data included information about maternal health (the degree of obesity, associated complications of birth, anemia, and type of birth) and neonatal status (birth weight, gestational age, associated diseases and Apgar score).
Results:
A higher incidence of IUGR, as well as an increased frequency of infants who needed intensive care after birth, a higher rate of cesarean surgery and a higher frequency of thromboembolic complications were observed in patients with associated obesity.
Conclusions:
Complications grow both in number and severity with increasing obesity. Diagnosis of the fetuses with IUGR is important for the monitoring and management of the pregnancy associated with obesity and it involves a close collaboration between obstetrician, family physician and neonatologist.
More Related Videos
11:44A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
Published on: September 27, 2017
14:40Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
Published on: October 25, 2015
Related Concept Videos
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Obesity
Teratogenicity
Diabetes Mellitus: Type 2 and Gestational
Drug Dosing: Obese Patients
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion