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Maxillary solitary recurrent plasmacytoma: a case report
Chirurgia (Bucharest, Romania : 1990)
|October 26, 2013
Summary
Solitary plasmacytoma, a rare plasma cell neoplasm, presents diagnostic challenges. This case highlights the effectiveness of combined surgical and chemotherapy approaches for managing multiple, temporally separated tumors.
Area of Science:
- Oncology
- Hematology
- Neoplasia
Background:
- Solitary plasmacytoma is a rare monoclonal gammopathy characterized by a solitary plasma cell tumor.
- It can manifest in bone marrow or extramedullary sites, often presenting with vague symptoms.
- Early diagnosis is crucial due to the significant risk of progression to multiple myeloma.
Observation:
- A 52-year-old patient presented with multiple, temporally separated solitary plasmacytomas over 14 years.
- Medullary evaluations showed no signs of plasma cell infiltration.
- Maxillary tumor required surgical excision, preserving the eye bulb and orbital function.
Findings:
- Initial chemotherapy response was followed by the need for surgical resection and reconstruction.
- The case demonstrates successful management of a rare, multifocal solitary plasmacytoma.
- Surgical intervention achieved functional and aesthetic rehabilitation in a complex maxillary case.
Implications:
- Combined surgical and chemotherapy treatment can be beneficial for managing solitary plasmacytoma.
- Aggressive surgical management may be necessary for localized, persistent, or recurrent disease.
- This case underscores the importance of multidisciplinary approaches in rare oncological entities.
