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Updated: May 6, 2026
04:18
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
750
Breech presentation at delivery: a marker for congenital anomaly?
D Mostello1, J J Chang2, F Bai2
1Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Women's Health, School of Medicine, Saint Louis University, St Louis, MO, USA.
Summary
Infants born in breech presentation are more likely to have congenital anomalies. This association highlights the need for careful examination of breech-delivered babies for malformations.
Area of Science:
- Obstetrics and Gynecology
- Pediatric Medicine
- Medical Genetics
Background:
- Congenital anomalies represent a significant concern in neonatal health.
- Breech presentation, a deviation from the typical cephalic presentation, is a known risk factor for adverse birth outcomes.
Purpose of the Study:
- To investigate the association between breech presentation at birth and the occurrence of congenital anomalies.
- To determine if breech presentation serves as a marker for underlying malformations.
Main Methods:
- A population-based retrospective cohort study of 460,147 singleton live births.
- Utilized the Missouri Birth Defects Registry for comprehensive congenital anomaly data.
- Employed multivariable binary logistic regression to analyze adjusted odds ratios (aORs) and 95% confidence intervals (CIs).
Main Results:
- Infants with breech presentation had a higher incidence of congenital anomalies (11.7%) compared to those with cephalic presentation (5.1%).
- This association was observed in both full-term (9.4% vs. 4.6%) and preterm (20.1% vs. 11.6%) births.
- The relationship between breech presentation and congenital anomaly was stronger in full-term births (aOR 2.09) than in preterm births (aOR 1.40).
Conclusions:
- Breech presentation at delivery is a significant indicator for the presence of congenital anomalies.
- Neonates delivered in breech presentation warrant thorough screening for malformations.
- Early identification of congenital anomalies in breech-presenting infants can facilitate timely medical intervention.
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