Related Experiment Video

Updated: May 6, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
06:29

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

10.4K

[Magnetic resonance tomography in diagnostics of coronary heart disease]

I S Zhelezniak, G E Trufanov, S D Rud'

    Klinicheskaia Meditsina
    |October 29, 2013
    PubMed

    Insights

    Contrast-enhanced MRI reveals myocardial perfusion defects in angina and identifies scar tissue in post-myocardial infarction patients. These findings correlate with impaired left ventricular contractility in coronary heart disease.

    Area of Science:

    • Cardiovascular Imaging
    • Cardiac Magnetic Resonance Imaging
    • Myocardial Perfusion Imaging

    Context:

    • Coronary heart disease (CHD) diagnosis and management rely on accurate assessment of myocardial ischemia and infarction.
    • Non-invasive imaging techniques are crucial for evaluating structural and functional changes in the heart.

    Purpose:

    • To investigate the utility of contrast-enhanced magnetic resonance tomography (1.5 Tl) in assessing myocardial perfusion and tissue characteristics in patients with coronary heart disease.
    • To correlate imaging findings with clinical manifestations such as angina of effort and post-infarction cardiosclerosis.

    Summary:

    • Contrast-enhanced MRI (1.5 Tl) in 101 CHD patients demonstrated that angina of effort is linked to disturbed myocardial perfusion, indicated by hypointense signals during initial contrast passage.
    • Acute myocardial infarction patients showed defective perfusion, T2-weighted hyperintense edematous regions, and delayed contrast enhancement at infarct sites.
    • Post-infarction cardiosclerosis was associated with hyperintense delayed contrast enhancement, reflecting myocardial scarring. Impaired local contractility, related to ischemia and scarring, led to reduced overall left ventricular function.

    Impact:

    • This study highlights the capability of contrast-enhanced MRI to detect and differentiate perfusion abnormalities, edema, and scar tissue in various stages of coronary heart disease.
    • Findings provide insights into the relationship between myocardial damage, perfusion deficits, and impaired cardiac function, aiding in risk stratification and treatment planning.
    • The results underscore the value of advanced MRI techniques in comprehensively evaluating the consequences of coronary heart disease on myocardial structure and function.

    More Related Videos

    Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking07:21

    Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking

    Published on: February 12, 2011

    14.1K
    Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse12:24

    Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

    Published on: June 20, 2014

    9.4K

    Related Concept Videos

    Imaging Studies for Cardiovascular System IV: CMRI01:21

    Imaging Studies for Cardiovascular System IV: CMRI

    Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
    542
    Magnetic Resonance Imaging01:24

    Magnetic Resonance Imaging

    Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
    7.6K
    Imaging Studies for Cardiovascular System V: CT01:28

    Imaging Studies for Cardiovascular System V: CT

    Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
    674
    Acute Coronary Syndrome III: Diagnostic Studies01:30

    Acute Coronary Syndrome III: Diagnostic Studies

    Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
    502
    Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

    Mitral Stenosis II: Clinical features and Diagnostic Tests

    Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
    565
    Imaging Studies IV: Magnetic Resonance Imaging01:27

    Imaging Studies IV: Magnetic Resonance Imaging

    Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
    432