Related Experiment Video
Updated: May 6, 2026

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System
Published on: April 23, 2021
Excessive adiposity and sedentary lifestyles are prevalent in cancer patients; a pilot study
Ana Isabel Almeida1, Dina Raquel João, Andreia Rolão
1Unidade de Nutriçao e Metabolismo. Instituto de Medicina Molecular. Faculdade de Medicina da Universidade de Lisboa.
Abstract:
Cancer aetiology is multifactorial; risk factors comprise obesity, central adiposity, physical inactivity and excessive/ deficient intake of foods and/or nutrients with procarcinogenic/ protective effects. We aim to analyze the pattern of nutritional status, food intake and physical activity in a cohort of cancer patients. This pilot crosssectional study was conducted in 64 outpatients referred for Radiotherapy. Nutritional parameters evaluated: BMI, waist circumference, body composition by tetrapolar bioimpedance (Xitron®). Usual food intake was collected with a short food frequency questionnaire and physical activity was assessed with Jacksons' questionnaire. Overweight/obesity and excessive body fat mass prevalence was of 53% and 61%, respectively. Central obesity, which indicates moderate/high cardio-metabolic risk, was found in 78% of patients. Food frequency analysis showed a poor intake in vegetables and a high intake in meat and carbohydrates. Physical inactivity was prevalent. This pilot study in cancer patients, showed a high prevalence of overweight/obesity, excessive fat mass and central obesity, simultaneously with sedentary lifestyles and an inadequate diet, poor in protective foods and excessive in deleterious ones. Thus, these patients exhibit a high risk pattern for cancer development and for a poorer prognosis. The implementation of measures to promote balanced and protective diets and to encourage physical activity practice is urgently needed.
Related Concept Videos
Cancer Prevention
Some...
Cancer Prevention
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Cancer Survival Analysis
Obesity
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

