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Updated: May 6, 2026

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Surgical Correction for Pediatric Epiblepharon and Trichiasis
Published on: July 8, 2025
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Esotropia surgery in children with Down syndrome
Claudio I Perez1, Francisca Zuazo, Mario T Zanolli
1Fundación Oftalmológica los Andes, Santiago, Chile; Universidad de los Andes, Santiago, Chile.
Summary
Children with Down syndrome (DS) undergoing esotropia surgery achieved good postoperative alignment. Surgical success rates in DS patients were comparable to those without DS, indicating effective treatment outcomes.
Area of Science:
- Ophthalmology
- Genetics
- Pediatric Surgery
Background:
- Esotropia is a common strabismus in children.
- Down syndrome is associated with various health conditions, including ocular abnormalities.
- Surgical correction is a primary treatment for esotropia.
Purpose of the Study:
- To compare postoperative alignment outcomes in children with and without Down syndrome after surgical correction of esotropia.
- To evaluate the efficacy of standard surgical techniques for esotropia in patients with Down syndrome.
Main Methods:
- Retrospective review of medical records for patients with Down syndrome who had esotropia surgery (1992-2012).
- Inclusion criteria: age 8 months to 17 years at surgery.
- Comparison with a randomly selected, age-matched control group without Down syndrome.
Main Results:
- 17 patients with Down syndrome and 27 controls were analyzed.
- Groups had similar follow-up durations and preoperative deviation magnitudes.
- Postoperative alignment success at 6 months was 76% for Down syndrome patients and 85% for controls.
Conclusions:
- Good surgical outcomes for esotropia were achieved in children with Down syndrome.
- The surgical technique yielded comparable results in patients with and without Down syndrome.
- This suggests that standard surgical approaches are effective for esotropia in children with Down syndrome.

