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Updated: May 6, 2026

Murine Flexor Tendon Injury and Repair Surgery
Published on: September 19, 2016
The growth factors involved in flexor tendon repair and adhesion formation
O A Branford1, B R Klass, A O Grobbelaar
1Institute for Plastic Surgery Research and Education, The Royal Free Hospital, London, UK.
Abstract:
Flexor tendon injuries remain a significant clinical problem, owing to the formation of adhesions or tendon rupture. A number of strategies have been tried to improve outcomes, but as yet none are routinely used in clinical practice. Understanding the role that growth factors play in tendon repair should enable a more targeted approach to be developed to improve the results of flexor tendon repair. This review describes the main growth factors in tendon wound healing, and the role they play in both repair and adhesion formation.
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