[Left ventricular thrombus formation in a patient with normal ejection fraction].

Area of Science:

• Cardiology
• Cardiovascular Medicine
• Thrombosis Research

Background:

• Left ventricular (LV) thrombi are commonly associated with impaired LV function, seen in conditions like dilated cardiomyopathy, LV aneurysm, or post-myocardial infarction.
• Thrombus formation within a normally functioning LV is exceptionally rare, challenging typical etiological understanding.

Observation:

• A patient presented with transient loss of consciousness and diagnosed cerebral embolism.
• Echocardiography revealed a pedunculated and hypermobile mass in the LV apex.
• The mass was surgically excised due to significant embolic risk.

Findings:

• Histopathological examination confirmed the LV mass to be a thrombus.
• This case demonstrates LV thrombus formation occurring despite preserved LV systolic function (normal ejection fraction).

Implications:

• This case underscores the possibility of LV thrombus formation even in the absence of overt systolic dysfunction.
• Clinicians should consider LV thrombi in the differential diagnosis of embolic events, regardless of perceived LV function.
• Further research may be warranted to elucidate the specific mechanisms underlying thrombus formation in normofunctional left ventricles.