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Assessment of liver function in two groups of outdoor workers exposed to arsenic
Teodorico Casale1, Maria Valeria Rosati, Manuela Ciarrocca
1Unit of Occupational Medicine, Department of Anatomy, Histology, Legal Medicine and Orthopedics, University of Rome "Sapienza", Viale Regina Elena 336, 00161, Rome, Italy, info@spinoff-sipro.it.
Purpose:
To evaluate whether the exposure to arsenic (As) causes alterations of liver enzymes in two groups of outdoor workers.
Methods:
Total urinary As and the levels of AST/GOT, ALT/GPT, and GGT were measured on 80 traffic policemen and 50 police drivers. Personal air samples were obtained for assessing the exposure to As on a subgroup of 20 traffic policemen and 20 police drivers.
Results:
Mean values of personal exposure to As, urinary As, AST/GOT, and ALT/GPT were significantly higher in traffic policemen than in the police drivers. Multiple linear regression models showed associations between urinary As and airborne As, ALT/GPT and the job variables, and BMI and urinary As.
Conclusions:
These findings contribute toward the evaluation of the hepatic effects of exposure to As in the urban workers.
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