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Fast, single-step, and surfactant-free oligonucleotide modification of gold nanoparticles using DNA with a positively
Ron Gill1, Kristian Göeken, Vinod Subramaniam
1Nanobiophysics Group, MIRA Institute of Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands. r.gill@utwente.nl.
Chemical Communications (Cambridge, England)
|October 30, 2013
Abstract:
Fast modification of large gold nanoparticles with DNA is achieved by using DNA with a polycationic tail. The conjugated DNA is available for specific hybridization, and therefore can be used for DNA-based assays or for constructing nanoparticle superstructures based on DNA hybridization.
