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Related Experiment Video

Updated: May 6, 2026

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging

Published on: December 9, 2021

Time-resolved angiography using inflow subtraction (TRAILS).

Daniel Kopeinigg¹, Roland Bammer

¹Department of Radiology, Stanford University, Stanford, California, USA.

Magnetic Resonance in Medicine

|October 30, 2013

Summary

This summary is machine-generated.

A new angiography technique, Time-Resolved Angiography using InfLow Subtraction (TRAINS), provides detailed whole-head vascular imaging in under 5 minutes. This method offers excellent vessel delineation and hemodynamic information in healthy volunteers.

Keywords:

4D MRA SPGR angiography arterial spin labeling noncontrast enhanced noninvasive time resolved

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Transthoracic Echocardiographic Examination in the Rabbit Model

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Published on: June 1, 2019

Area of Science:

Medical Imaging
Neuroimaging
Vascular Imaging

Background:

Arterial spin labeling (ASL) is a non-invasive MRI technique for assessing blood flow.
Current ASL methods may have limitations in temporal resolution for dynamic vascular imaging.
Time-resolved angiography is crucial for understanding complex blood flow dynamics.

Purpose of the Study:

Introduce a novel pseudo-continuous ASL method: Time-Resolved Angiography using InfLow Subtraction (TRAINS).
Acquire time-resolved whole-head angiographic datasets in healthy volunteers.
Achieve clinical feasibility within a scan time of less than 5 minutes.

Main Methods:

Utilized TRAINS in conjunction with sliding window reconstruction.
Achieved a temporal resolution of 7.2 ms.
Obtained a low temporal footprint of 432 ms for data acquisition.

Main Results:

Demonstrated excellent vessel delineation compared to time-of-flight MRA.
Successfully identified normal vascular variations, including the Circle of Willis (CoW).
Quantified blood transit time by measuring signal intensities in vascular segments.

Conclusions:

TRAINS enables high temporal and spatial resolution hemodynamic whole-head imaging in healthy volunteers.
This technique shows promise for feasibility in clinical settings.
Further studies are warranted in patients with vascular diseases to explore diverse flow patterns and longer transit times.