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Related Concept Videos

Pathophysiology of Vomiting01:22

Pathophysiology of Vomiting

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Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
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Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
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Pyloric Obstruction01:11

Pyloric Obstruction

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Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
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Gastrointestinal Motility Disorders01:20

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Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Irritable Bowel Syndrome

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DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility...
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Related Experiment Video

Updated: May 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Cyclic vomiting syndrome: a common, underrecognized disorder.

Thais Brown Tonore1, Danielle C Spree, Thomas Abell

  • 1Department of Family Medicine, University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi.

Journal of the American Association of Nurse Practitioners
|October 31, 2013
PubMed
Summary

Prompt recognition and treatment of cyclic vomiting syndrome (CVS) can abort episodes and reduce hospitalizations. Early diagnosis and appropriate management, including lifestyle changes and migraine therapies, are key for effective CVS treatment.

Keywords:
Childrendisabilitymigrainespharmacotherapy

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Last Updated: May 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

19.1K

Area of Science:

  • Gastroenterology
  • Neurology

Background:

  • Cyclic vomiting syndrome (CVS) is a debilitating condition characterized by recurrent, stereotypical episodes of nausea and vomiting.
  • Accurate diagnosis and effective management strategies for CVS are often lacking, leading to significant patient morbidity and healthcare costs.

Purpose of the Study:

  • To enhance the recognition of cyclic vomiting syndrome (CVS).
  • To present effective symptom assessment and treatment strategies for CVS.

Main Methods:

  • Review of clinical experience.
  • Analysis of pediatric, gastroenterological, and emergency medicine research.
  • Examination of survey data and literature reviews on CVS.

Main Results:

  • Prompt diagnosis and appropriate treatment can abort CVS episodes.
  • Inappropriate treatment often leads to hospitalization due to symptom complications.
  • Lifestyle modifications, prophylactic and abortive migraine therapies, and supportive care are crucial for prevention.

Conclusions:

  • Improved recognition, diagnosis, and treatment of CVS can significantly improve patient symptom management.
  • Effective management of CVS may reduce associated morbidity and hospitalization costs.
  • Early intervention and comprehensive care are vital for managing cyclic vomiting syndrome.