Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.7K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.7K
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

38
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
38
Dementia01:30

Dementia

696
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
696
Dementia l: Introduction01:22

Dementia l: Introduction

35
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
35
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

402
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
402
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

1.3K
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Health economic evaluation studies in India's traditional system of medicine (Ayush): A scoping review.

Journal of family medicine and primary care·2026
Same author

Out-of-pocket expenditure experienced by couples seeking In Vitro Fertilization (IVF) services at tertiary care facilities in India.

PloS one·2026
Same author

Risk and protective factors for cognitive decline in older adults from a nationally representative sample in India: Results from the LASI-DAD.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Out of pocket expenditure incurred by couples seeking infertility services at tertiary level facilities in India.

The Indian journal of medical research·2026
Same author

Interventions for improving resilience among healthcare workers: a systematic map.

Npj mental health research·2026
Same author

A functional MRI and magnetoencephalography study of the cognitive modulatory effect of transcranial direct current stimulation in early Alzheimer's disease.

Frontiers in human neuroscience·2026

Related Experiment Video

Updated: May 6, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.0K

Identifying elders with neuropsychiatric problems in a clinical setting.

Shilpa Sadanand1, Prafulla Shivakumar, N Girish

  • 1Geriatric Clinic and Services, National Institute of Mental Health and Neurosciences, Bangalore, India.

Journal of Neurosciences in Rural Practice
|November 1, 2013
PubMed
Summary

A new screening tool, ICE-E, effectively identifies neuropsychiatric issues and medical comorbidities in older adults. This brief assessment aids early detection and treatment planning for elderly patients.

Keywords:
Comorbidityelderlyinstruments screeningmental healthneuro-psychiatric problems

More Related Videos

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

13.9K
Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

6.3K

Related Experiment Videos

Last Updated: May 6, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.0K
Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

13.9K
Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

6.3K

Area of Science:

  • Geriatric Medicine
  • Neuropsychiatry
  • Public Health

Background:

  • Elderly populations face multiple health challenges, necessitating early detection and intervention.
  • Neuropsychiatric disorders and comorbid medical conditions are prevalent in older adults.
  • Comprehensive screening is crucial for managing the complex health needs of the elderly.

Purpose of the Study:

  • To comprehensively identify older adults with neuropsychiatric problems, including dementia and comorbid medical conditions.
  • To evaluate the utility of a novel screening instrument in a geriatric clinic setting.
  • To facilitate early detection and treatment initiation for common elderly health issues.

Main Methods:

  • A 2-year screening of 5,260 outpatients aged 60+ at NIMHANS.
  • Utilized validated instruments: General Health Questionnaire (GHQ-12), AD8, psychoses screener, neurological screener, and medical comorbidity checklist.
  • Probable clinical diagnoses made by medical personnel based on ICD-10 criteria.

Main Results:

  • Over 50% experienced psychological distress (GHQ-12), 20.1% had probable cognitive impairment (AD8), and 17% showed psychosis symptoms.
  • More than 65% had neurological issues; common psychiatric disorders included psychotic disorders (22.0%), mood disorders (21.4%), and dementia (14.4%).
  • Nearly 80% had medical comorbidities like hypertension (36.4%) and visual impairment (31.8%) alongside psychiatric conditions.

Conclusions:

  • The Instruments for Comprehensive Evaluation of the Elderly (ICE-E) is a brief, easy-to-administer tool.
  • ICE-E systematically detects neuropsychiatric problems and medical comorbidities in the elderly.
  • The instrument improves decision-making, even for non-medical personnel, enhancing geriatric care.