Related Experiment Video
Updated: May 6, 2026
10:46
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
10.3K
Vitamin D deficiency in the sunshine state
Umabala Pasupala1, Debra Hain, Rute Paixao
1Cleveland Clinic Florida, Department of Hypertension/Nephrology, Weston, FL, USA.
Summary
Vitamin D deficiency is common in chronic kidney disease (CKD) patients, particularly in the southern US. Early identification of this vitamin D deficiency is crucial for implementing preventative strategies and mitigating adverse health effects.
Area of Science:
- Nephrology
- Endocrinology
- Nutritional Science
Background:
- Vitamin D offers significant skeletal and extraskeletal health benefits.
- Chronic kidney disease (CKD) is linked to increased risk of vitamin D deficiency, even in early stages.
- Vitamin D deficiency can lead to detrimental health outcomes in CKD patients.
Purpose of the Study:
- To determine the prevalence of vitamin D deficiency in CKD patients residing in the southern United States.
- To inform early identification and preventative strategies for vitamin D deficiency in this population.
Main Methods:
- This study focuses on understanding the prevalence of vitamin D deficiency.
- The target population is individuals with chronic kidney disease.
- Geographic focus is on the southern areas of the United States.
Main Results:
- The prevalence of vitamin D deficiency in the studied CKD population requires further investigation.
- Data on the specific prevalence in the southern US CKD population is essential.
Conclusions:
- Understanding vitamin D deficiency prevalence in southern US CKD patients is key.
- This knowledge supports timely intervention and preventative care for CKD patients.
- Addressing vitamin D deficiency can improve patient outcomes and mitigate complications.
Related Concept Videos
01:23Role of Skin in Vitamin D Synthesis
8.2K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.2K
01:30Vitamins
2.7K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.7K
01:25Role of Vitamins in Maintaining Bone Health
5.1K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.1K
01:25Jaundice
48
Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...
48
01:29Decreased Body Temperature
1.2K
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
1.2K
01:19Multiple Sclerosis l: Introduction
32
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
32