Relation of substance P to catecholamine metabolism and stress

This paper gives a survey on selected topics of Substance P (SP) research. In particular, it presents results on the function of SP in sympathetic ganglia (including the adrenal medulla) and discusses interconnections between the influence of SP on the catecholamine system and the role of SP both in the nervous and the circulatory system. Furthermore, the paper deals with the current developments in the field of "SP-ergic" drugs.