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On-demand therapy for hereditary angioedema

Jonathan A Bernstein1

  • 1Allergy Section, Division of Immunology, Department of Internal Medicine, College of Medicine, University of Cincinnati, 3255 Eden Avenue, Suite 350 ML#563, Cincinnati, OH 45267-0563, USA.

Immunology and Allergy Clinics of North America
|November 2, 2013
PubMed

Consensus guidelines on hereditary angioedema (HAE) recommend that all patients have access to on-demand treatment of acute attacks. A recent patientcentric guideline recommended that at least 2 on-demand therapies be available because patients often have heterogeneous responses to different medications. Self-administration of therapeutic agents, or administration under supervision by a health care provider in the home setting, is the preferred treatment approach. Future studies are needed to show the benefits of acute on-demand therapies at improving quality of life and reducing morbidity and mortality in patients with HAE.

Keywords:
BerinertEcallantideGuidelinesHereditary angioedemaIcatibantOn-demand therapiesRuconest

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