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Related Concept Videos

Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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Increased Body Temperature01:25

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Encephalitis l: Introduction01:19

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Arboviral Encephalitis01:25

Arboviral Encephalitis

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
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Viral Meningitis01:18

Viral Meningitis

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Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Related Experiment Video

Updated: May 6, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

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Fever and neurologic conditions.

Aisha T Liferidge1, Janaé E P Dark

  • 1Department of Emergency Medicine, George Washington University School of Medicine, 2120 L Street Northwest, Suite 450, Washington, DC 20037, USA.

Emergency Medicine Clinics of North America
|November 2, 2013
PubMed
Summary

Fever with neurologic symptoms requires broad differential diagnosis for accurate management. Thorough history and physical exams, including collateral information, are crucial for prompt diagnosis and effective treatment of these complex cases.

Keywords:
FeverNeurologic abnormalitiesNeurologic conditions

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Area of Science:

  • Neurology
  • Infectious Disease

Background:

  • Neurologic conditions present with altered mental status or focal findings.
  • Fever in conjunction with neurologic abnormalities can stem from primary neurological issues or non-central nervous system origins.

Purpose of the Study:

  • To outline optimal management strategies for neurologic conditions associated with fever.
  • To emphasize the importance of clinical suspicion and differential diagnosis in these cases.

Main Methods:

  • Review of diagnostic approaches for neurologic abnormalities and fever.
  • Emphasis on thorough patient history and physical examination.
  • Highlighting the utility of collateral information from external sources.

Main Results:

  • Effective management hinges on high clinical suspicion.
  • A broad differential diagnosis aids in rapid recognition.
  • Accurate diagnosis is often facilitated by comprehensive history, physical examination, and collateral data.

Conclusions:

  • Prompt and accurate diagnosis of neurologic conditions with fever is critical for effective treatment.
  • Clinical vigilance and a systematic diagnostic approach are paramount.