Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Precipitation and Co-precipitation01:17

Precipitation and Co-precipitation

4.9K
Precipitation and coprecipitation methods can be used to separate a mixture of ions in a solution. In qualitative inorganic analysis, ions that form sparingly soluble precipitates with the same reagent are separated based on the differences in solubility products. For example, consider the separation of Cu(II) and Fe(II) ions by precipitation as insoluble sulfides. First, copper(II) sulfide is precipitated by the addition of acidic H2S, where the dissociation of H2S is suppressed. Adding H2S...
4.9K
Electrodeposition01:08

Electrodeposition

2.8K
Electrodeposition is a technique used to separate an analyte from interferents by electrochemical processes. Here, the analyte is a metal ion that can be deposited on an electrode immersed in the sample solution. The electrochemical setup consists of an anode and a cathode. When an electric current is applied to the setup, oxidation occurs at the anode. At the cathode, which consists of a large metal surface, metal ions undergo reduction and deposit onto the surface.
Electrodeposition can...
2.8K
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

1.3K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.3K
Ladder Diagrams: Complexation Equilibria01:07

Ladder Diagrams: Complexation Equilibria

744
Ladder diagrams are useful for evaluating equilibria involving metal-ligand complexes. The vertical scale of the ladder diagram represents the concentration of unreacted or free ligand, pL. The horizontal lines on the scale depict the log of stepwise formation constants for metal-ligand complexes and indicate the dominant species in all the regions.
The formation constant, K1, for the formation of Cd(NH3)2+ complex from cadmium and ammonia is 3.55 × 102. Log K1 (i.e. pNH3) is 2.55, and...
744
Phase II Reactions: Miscellaneous Conjugation Reactions01:19

Phase II Reactions: Miscellaneous Conjugation Reactions

477
Phase II biotransformations are detoxification mechanisms that conjugate xenobiotics with endogenous substances, neutralizing their toxicity.
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...
477
Corrosion02:49

Corrosion

21.8K
The degradation of metals due to natural electrochemical processes is known as corrosion. Rust formation on iron, tarnishing of silver, and the blue-green patina that develops on copper are examples of corrosion. Corrosion involves the oxidation of metals. Sometimes it is protective, such as the oxidation of copper or aluminum, wherein a protective layer of metal oxide or its derivatives forms on the surface, protecting the underlying metal from further oxidation. In other cases, corrosion is...
21.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of a crystalline distannylene-stabilized quinoxaline radical anion.

Chemical communications (Cambridge, England)·2026
Same author

<i>N</i>-(3,5-Di-chloro-4-meth-oxy-phen-yl)acetamide.

IUCrData·2026
Same author

Synthesis of Difluoroethanols by the Unexpected Nucleophilic Addition of Lactones to Difluoromethyl Ketones and Dimerization of Difluoromethyl Ketones.

The Journal of organic chemistry·2026
Same author

HFIP-Induced Formation of <i>O</i>-Aryl Oxyallyl Cation and Nucleophilic Addition with Sodium Sulfinate Salt.

The Journal of organic chemistry·2026
Same author

Imparting Water Solubility and Aqueous Electrochemical Activity to Ferrocene upon Confinement.

Inorganic chemistry·2026
Same author

Electroanalytical Methods to Establish the Role of Buffer and Electrolyte Components in Water Denitrification Using a Copper-Based Bioinspired Electrocatalyst.

ACS measurement science au·2026

Related Experiment Video

Updated: May 6, 2026

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
06:52

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Published on: April 28, 2023

2.3K

Copper β-trinitrocorrolates.

Manuela Stefanelli1, Sara Nardis, Frank R Fronczek

  • 1Dipartimento di Scienze e Tecnologie Chimiche, Università di Roma Tor Vergata, 00133 Roma, Italy.

Journal of Porphyrins and Phthalocyanines
|November 2, 2013
PubMed
Summary
This summary is machine-generated.

This study details a regioselective β-nitration method for corrole macrocycles using silver nitrite and sodium nitrite. The efficient nitration system yields mono-, di-, and tri-nitro derivatives, expanding synthetic possibilities for these complex molecules.

Keywords:
AgNO2corrolenitrationβ-functionalization

More Related Videos

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by GalliumIII and H3 5,10,15-trispentafluorophenylcorroles
09:00

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by GalliumIII and H3 5,10,15-trispentafluorophenylcorroles

Published on: March 18, 2015

11.1K
Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

9.7K

Related Experiment Videos

Last Updated: May 6, 2026

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
06:52

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders

Published on: April 28, 2023

2.3K
An In Vitro Enzymatic Assay to Measure Transcription Inhibition by GalliumIII and H3 5,10,15-trispentafluorophenylcorroles
09:00

An In Vitro Enzymatic Assay to Measure Transcription Inhibition by GalliumIII and H3 5,10,15-trispentafluorophenylcorroles

Published on: March 18, 2015

11.1K
Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

9.7K

Area of Science:

  • Organic Chemistry
  • Macromolecular Chemistry
  • Synthetic Chemistry

Background:

  • Corrole macrocycles possess reduced symmetry, potentially leading to numerous regioisomers during functionalization.
  • Previous work established AgNO2/NaNO2 as an efficient nitrating system for corrole derivatives.

Purpose of the Study:

  • To comprehensively investigate the scope and limitations of the β-nitration reaction on corrole macrocycles.
  • To explore the synthesis of tri-nitrocorrole derivatives and characterize their regioisomers.

Main Methods:

  • Utilized a silver nitrite/sodium nitrite (AgNO2/NaNO2) system for β-nitration of TtBuCorrH3 (a model corrole).
  • Employed varying excesses of nitrating agents to control the degree of functionalization.
  • Characterized products using techniques including X-ray crystallography.

Main Results:

  • Achieved regioselective mono- and di-nitration of corrole free base and copper complexes.
  • Synthesized the 2,3,17-trinitro-TtBuPCorrCu isomer in 25% yield, alongside the 3,8,17-trinitro isomer.
  • Re-characterized bis-substitution products, confirming the structure of copper 3,8-dinitrocorrolate.

Conclusions:

  • The AgNO2/NaNO2 nitration system is effective for controlled β-functionalization of corroles.
  • Higher nitrating agent concentrations can lead to tri-nitration but risk macrocycle decomposition.
  • This method provides access to specifically substituted nitrocorrole derivatives.